A new solution to an old problem: Try a TSEC

Keeping bones healthy through the menopausal transition is important, and it's not always clear what might be the best way to do that for each woman. One new approach is to use a compound approach called TSEC: "TISSUE SELECTIVE ESTROGEN COMPLEX". This approach is to pair an estrogen with a selective estrogen receptor modulator. The combination leaves the medication with a fine tuned product that has the ability to react to some estrogen sites and turn off others. The Women's Health Practice Research team has been involved in some of the trials of this nature and data is just being released from some of these trials. in the SMART trial (Selective estrogen Menopause and Response to Therapy Trial) Bazedoxifene was pared with a conjugated equine estrogen as a potential comprehensive bone and menopausal therapy. Bazedoxifene is an investigational nonsteroidal indole-based estrogen agonist/antagonist (given alone called a SERM) that is being developed as a daily oral drug for the prevention and treatment of postmenopausal osteoporosis. Bazedoxifene can bind to both ERα and ERß, with slightly more affinity for ERα and serves as a competitive inhibitor of 17ß-estradiol at each receptor. Thus it is anti-breast proliferation. The newly released study showed that when used for two years women were able to increase their spine and hip bone density.

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Passing Your Uterine Lining, Menstrual Period Norms

Decidual Cast Periods can be fairly easy, passing some tissue at a time, or off can come the whole lining in one piece called a decidual cast. Generally the lining of the uterus is only 6-8 mm thick at the time of the menstrual period, and it is shed gradually, a few cells at a time. The decidual cast is when the entire lining passes spontaneously. It's not uncommon, but it usually both uncomfortable, and alarming to some. But us women are designed to have some sort of periods Or Not? We have to pass tissue each month. Or Not? Are they good for us? Or Not? Do we want them? Or Not? Is this something that is individual? Or Not? It's a complex topic that I will be discussing a lot over my time in this blog. So lets start with basics: How much do we bleed and what are we loosing, and just what was this that the patient passed? And another basic: track your periods, and the Women's Health Practice site http://www.womenshealthpractice.com/media/pdf/menstrual_chart.pdf you...

Post-Endometrial Ablation Syndrome

If you have had an endometrial ablation and have developed symptoms of pelvic pain you might have post endometrial ablation syndrome. What is post-endometrial ablation syndrome? It is a constellation of symptoms due to entrapped blood or tissue within a uterus that has previously undergone an endometrial ablation. We are able to diagnose this at Women's Health Practic e but occasionally other conditions are causing similar symptoms. Other complications of endometrial ablation include pregnancy, risks from pre-existing conditions such as a polyp or fibroid, an infection of the uterus, or a pregnancy. If you have had a tubal ligation then it is possible that the condition could be post-ablation tubal sterilization syndrome. The ablation procedure is designed to destroy all lining tissue, but in fact there is no way to confirm the completeness of the ablation. It is thought that either residual or regrowth of the tissue is producing the symptoms of post-endometrial ablation syndrom...

You Have an IUD: But a Positive Pregnancy Test

Fortunately IUD pregnancy failures are rare. But if you have an IUD for contraception, and you get a positive pregnancy test, you probably ask yourself, what next? Well, make your gyno appointment promptly, this is a condition that is not typically an emergency, but it can be and it’s not handled over the phone or on a blog, or through self diagnosis! That being said, some researchers from University of Texas Southwestern Medical Center in Dallas decided to look back at over 4100 women who had IUDs and of those 42 cases who became pregnant in their institution, over about a year period of time, to help understand what these women could expect when they got to their gyno and what actually happened to their pregnancies. Accurate pregnancy diagnosis, pelvic examination, and pelvic ultrasound were the cornerstones of the evaluations. They had very specific ways they looked at their ultrasound to prove there was no pregnancy in the fallopian tube, or partially in the fallopian tube...

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