Endocervical Polyp In perimenoapsue and menopause taking estrogen can cause wide ranging side effects. However, the effects on the lining of the uterus is not one of the benefits. Estrogen can cause bleeding, spotting, polyps, precancer and even lining cancer of the uterus. In a new report we have found that rates of uterine cancers are going up. he study, published May 22, 2019 in the Journal of Clinical Oncology the information from NCI's Surveillance, Epidemiology, and End Results (SEER) database to evaluate trends in uterine cancer incidence rates for women overall and by race and ethnicity, geographic region, and biologic subtype , and found more aggressive and what used to be rare types of cancers of the uterus are increasing. Whether these things will occur will depend on many factors, including lifestyle, prior therapy, your diet , and your genetics. In the study it was thought that the biggest increases in uterine cancer, were due to cancers that ...