Mirena IUD and Uterine Fbroids

Uterine fibroids and what method of contraception you choose are two separate gynecologic issues, but if you have both there are many pros and cons to discover. The IUD first has to be inserted and there are some cases of uterine fibroids take up some space in the cavity of the uterus and it's possilbe that the IUD would be expelled after insertion. Typically we say that only about 2% of all IUDs are expelled in the first year after insertion. With uterine fibroids that expulsion rate could climb to over 10%. Your Mirena IUD can shrink your fibroids.It is known that the IUD can shrink the overall size of your uterus. Women who suffer from uterine fibroids need to get to their gyno and evaluate their reproductive plan. In a September 2010 issue of Contraception it was reported from Jiangsu, China that they have discovered that the progestin component, the levonorgestrel, may actually both suppress the growth and cause death of uterine fibroid cells! WoW! It is important to control the growth of this common uterine tumor as they can grow quite large and produce symptoms of pain as well as symptoms of heavy bleeding. These researchers have been studying the fine points of fibroid growth. We know that it's probably a chromosome glitch in a single uterine muscle cell that gets that fibroid cell's growth unleashed and causes a tumor to grow. So they did a study of cells in culture from twenty women with fibroids who had hysterectomy. They point out that the growth, based on active DNA (ok, for the accurate scientists, actual mRNA phase of growth) was more active in the progesterone (luteal, second half) of the menstrual cycle, but paradoxically the growth of fibroids is somewhat restricted during phases of pregnancy when progesterone is very high. So they tested the levonorgesterel progesterone that is in Mirena IUD (for discussion group pop on here). There theory was that the 20 mcg/ml that is leaked each day from the Mirena (LGN-IUS to the fancy people and for info outside the USA go to the other Mirena) is about 1000 times what a normal circulating progesterone level would be, and that in their cultures after only 72 hours the growth of those cells was decreased by 24%. Wow! And furthermore, in order for a fibroid not to grow, that progenitor abnormal cell must die! And apparently that is what our hormones regulate as well. And in this research trial the physicians were able to use large doses of the levonorgesterel to induce the death of these fibroid (leiomyoma) cells. So there is a whole bunch of complex growth regulating factors, including the newest growth regulator on the block: "survivin" (I love that name, almost want to buy a cat just to use it!) and how they interact with the exact gene make up of the cells of one's uterus that ultimately determines the survive or die of a fibroid cell. And survival instincts must be pretty good since the newest estimates are that up to 50% of all women will have uterine fibroids before they die! The best news yet is that these researchers aren't done, they have all sorts of new proposals to look at how this might work. And if the use of the progesterone containing IUD doesn't suffice to shrink your fibroids successfully, it may be time to try other therapies. Call 217-356-3736 if you live within range of central Illinois and wish to have this therapy, wish to participate in a research study, or if you are done with having children, you may be interested in office same day NovaSure endometrial ablation therapy.

Post-Endometrial Ablation Syndrome

If you have had an endometrial ablation and have developed symptoms of pelvic pain you might have post endometrial ablation syndrome. What is post-endometrial ablation syndrome? It is a constellation of symptoms due to entrapped blood or tissue within a uterus that has previously undergone an endometrial ablation. We are able to diagnose this at Women's Health Practic e but occasionally other conditions are causing similar symptoms. Other complications of endometrial ablation include pregnancy, risks from pre-existing conditions such as a polyp or fibroid, an infection of the uterus, or a pregnancy. If you have had a tubal ligation then it is possible that the condition could be post-ablation tubal sterilization syndrome. The ablation procedure is designed to destroy all lining tissue, but in fact there is no way to confirm the completeness of the ablation. It is thought that either residual or regrowth of the tissue is producing the symptoms of post-endometrial ablation syndrom...

Passing Your Uterine Lining, Menstrual Period Norms

Decidual Cast Periods can be fairly easy, passing some tissue at a time, or off can come the whole lining in one piece called a decidual cast. Generally the lining of the uterus is only 6-8 mm thick at the time of the menstrual period, and it is shed gradually, a few cells at a time. The decidual cast is when the entire lining passes spontaneously. It's not uncommon, but it usually both uncomfortable, and alarming to some. But us women are designed to have some sort of periods Or Not? We have to pass tissue each month. Or Not? Are they good for us? Or Not? Do we want them? Or Not? Is this something that is individual? Or Not? It's a complex topic that I will be discussing a lot over my time in this blog. So lets start with basics: How much do we bleed and what are we loosing, and just what was this that the patient passed? And another basic: track your periods, and the Women's Health Practice site http://www.womenshealthpractice.com/media/pdf/menstrual_chart.pdf you...

You Have an IUD: But a Positive Pregnancy Test

Fortunately IUD pregnancy failures are rare. But if you have an IUD for contraception, and you get a positive pregnancy test, you probably ask yourself, what next? Well, make your gyno appointment promptly, this is a condition that is not typically an emergency, but it can be and it’s not handled over the phone or on a blog, or through self diagnosis! That being said, some researchers from University of Texas Southwestern Medical Center in Dallas decided to look back at over 4100 women who had IUDs and of those 42 cases who became pregnant in their institution, over about a year period of time, to help understand what these women could expect when they got to their gyno and what actually happened to their pregnancies. Accurate pregnancy diagnosis, pelvic examination, and pelvic ultrasound were the cornerstones of the evaluations. They had very specific ways they looked at their ultrasound to prove there was no pregnancy in the fallopian tube, or partially in the fallopian tube...

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