Skip to main content

BRCA 1/2 Negative But May Still Be Genetically At Risk For Ovarian Cancer

Image
By
Gynos are still struggling to detect early stage ovarian cancer. The best we've come up with so far is to eliminate risk in those that genetically are at the highest risk. Women with BRCA 1 have about a 50% risk by age 50 and those with BRCA 2 have about an 85% lifetime risk of ovarian cancer. Ovarian removal in these women can reduce these risks down to extremely low rates. We now think that there is another genetic variant that helps explain the families of women who have risk but test negative for BRCA 1 and 2. This is the new test called PrOvar. It's very new, it's not widely available, and it's in the development phase.Remember, that pelvic examinations, close attention to how you feel, and in some cases pelvic ultrasounds, and when indicated, 3-D imaging will help identify women who already have disease. Once you have disease, Ova1 testing may be indicated to get proper treatment.
Labels:

Comments

Post a Comment

Thank you for your comments and questions. WE hope you will buy our book, https://www.gynogab.com/shop This blog is not intended to replace medical care, but is informational only. We hope you will become a follower or visit Womens Health Practice. We offer a variety of unique services including MonaLisa Touch, Coolsculpting, Labiaplasty, and Gynecoloigic Clinical Research Trials. For more information on menopause see

Popular posts from this blog

Post-Endometrial Ablation Syndrome

By
If you have had an endometrial ablation and have developed symptoms of pelvic pain you might have post endometrial ablation syndrome. What is post-endometrial ablation syndrome? It is a constellation of symptoms due to entrapped blood or tissue within a uterus that has previously undergone an endometrial ablation. We are able to diagnose this at Women's Health Practic e but occasionally other conditions are causing similar symptoms. Other complications of endometrial ablation include pregnancy, risks from pre-existing conditions such as a polyp or fibroid, an infection of the uterus, or a pregnancy. If you have had a tubal ligation then it is possible that the condition could be post-ablation tubal sterilization syndrome. The ablation procedure is designed to destroy all lining tissue, but in fact there is no way to confirm the completeness of the ablation. It is thought that either residual or regrowth of the tissue is producing the symptoms of post-endometrial ablation syndrom...
647 comments
Read more

Passing Your Uterine Lining, Menstrual Period Norms

By
Decidual Cast Periods can be fairly easy, passing some tissue at a time, or off can come the whole lining in one piece called a decidual cast. Generally the lining of the uterus is only 6-8 mm thick at the time of the menstrual period, and it is shed gradually, a few cells at a time. The decidual cast is when the entire lining passes spontaneously.  It's not uncommon, but it usually both uncomfortable, and alarming to some. But us women are designed to have some sort of periods  Or Not? We have to pass tissue each month. Or Not? Are they good for us? Or Not? Do we want them? Or Not? Is this something that is individual? Or Not? It's a complex topic that I will be discussing a lot over my time in this blog. So lets start with basics: How much do we bleed and what are we loosing, and just what was this that the patient passed? And another basic: track your periods, and the Women's Health Practice site http://www.womenshealthpractice.com/media/pdf/menstrual_chart.pdf you...
311 comments
Read more

You Have an IUD: But a Positive Pregnancy Test

By
Fortunately IUD pregnancy failures are rare. But if you have an IUD for contraception, and you get a positive pregnancy test, you probably ask yourself, what next? Well, make your gyno appointment promptly, this is a condition that is not typically an emergency, but it can be and it’s not handled over the phone or on a blog, or through self diagnosis! That being said, some researchers from University of Texas Southwestern Medical Center in Dallas decided to look back at over 4100 women who had IUDs and of those 42 cases who became pregnant in their institution, over about a year period of time, to help understand what these women could expect when they got to their gyno and what actually happened to their pregnancies. Accurate pregnancy diagnosis, pelvic examination, and pelvic ultrasound were the cornerstones of the evaluations. They had very specific ways they looked at their ultrasound to prove there was no pregnancy in the fallopian tube, or partially in the fallopian tube...
199 comments
Read more