Thursday, July 1, 2010

Endometriosis Quiets in Pregnancy, or Does it?

Have you previously been diagnosed with endometriosis, and told that "pregnancy is a good treatment." Wow, that probably was a set back, talk about expensive treatments! But it has always been thought that the high levels of progesterone in pregnancy would send endometriosis into dormancy. But not universally true. What progesterone tends to do is stimulate the enzyme that converts our main estrogen, estradiol, to a weak estrogen or estrone. Progesterone also can eliminate menstrual periods, quite the uterus so there are not so many contractions (this is perhaps the path by which progesterones prevent that retrograde menstruation), as well as the direct effects on the estrogen receptors in the nucleus of endometriosis cells. But apparently the lesions do quite in pregnancy, but don't really die off. So before you go and try to grow your own swim relay, basketball team, or entire soccer team in an effort to quell your recurrent endometriosis, maybe you better have a gab with your gyno!

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